Product Detail
Product NameHistone H3K36me3 Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
Immunogen TypePeptide
Immunogen DescA synthetic methylated peptide of human histone H3
Target NameHistone H3
ConjugateUnconjugated
Other NamesH3.4;H3/g;H3FT;H3t;HIST3H3;Histone H3;HIST1H3A
Accession NoUniprot:Q16695
GeneID:8290
Uniprot
Q16695
Gene ID
8290
Sdspage MW17KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using TriMethyl-Histone H3-K36 antibody.
Immunohistochemistry of paraffin-embedded Mouse brain using TriMethyl-Histone H3-K36 Rabbit pAb.
Immunofluorescence analysis of 293T cells using TriMethyl-Histone H3-K36 antibody.
Immunohistochemistry of paraffin-embedded Human breast cancer using TriMethyl-Histone H3-K36 Rabbit pAb.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
If you have published an article using product HW010, please notify us so that we can cite your literature.
et al,JACALIN-LECTIN LIKE1 Regulates the Nuclear Accumulation of GLYCINE-RICH RNA-BINDING PROTEIN7, Influencing the RNA Processing of
FLOWERING LOCUS C Antisense Transcripts and Flowering Time in Arabidopsis. In Plant Physiol on 2015 Nov by Jun Xiao, Chunhua Li,et al..PMID:26392261
, (2015),
PMID:
26392261
et al,AtJAC1 regulates nuclear accumulation of GRP7, influencing RNA processing of FLC antisense transcripts and flowering time in
Arabidopsis. In Plant Physiol on 2015 Nov by Jun Xiao, Chunhua Li, et al..PMID:26392261
, (2015),
PMID:
26392261
Yes
