Product Detail
                                
                                                                        Product NameHistone H3K79me2 Polyclonal Antibody
                                                                                 Host SpeciesRabbit
                                         ClonalityPolyclonal
                                        IsotypeIgG
                                        PurificationAffinity purification
                                        ApplicationsWB,IHC,IF
                                        Species ReactivityHuman,Mouse,Rat
                                                                                Immunogen TypePeptide
                                         Immunogen DescA synthetic peptide of human DiMethyl-Histone H3-K79
                                         Target NameHistone H3
                                         ConjugateUnconjugated
                                                                                 Other NamesH3.4;H3/g;H3FT;H3t;HIST3H3;Histone H3;HIST1H3A
                                        Accession NoUniprot:Q16695
GeneID:8290
                                        Uniprot
                                        Q16695
                                        
                                        Gene ID
                                        8290
                                        
                                                                                Sdspage MW17kDa
                                        Concentration1.0mg/ml
                                         FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
                                        StorageStore at -20˚C. Avoid freeze / thaw cycles.
                                                                                                                                                         
                                Application Details
                                WB	1:500 - 1:1000
IHC	1:50 - 1:100
IF	1:50 - 1:200
                             
                            
                                                                
                                    
                                    Western blot analysis of extracts of HeLa cells, using DiMethyl-Histone H3-K79 antibody.
                                 
                                                                
                                    
                                    Immunofluorescence analysis of 293T cells using DiMethyl-Histone H3-K79 antibody.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded rat testis using DiMethyl-Histone H3-K79 antibody.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded mouse testis using DiMethyl-Histone H3-K79 antibody.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded human mammary cancer using DiMethyl-Histone H3-K79 antibody.
                                 
                                                             
                            
                                Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. 
                            
                            
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