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Tau (Acetyl Lys174) Polyclonal Antibody#HW181

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Total Amount:$
Product Detail

Product NameTau (Acetyl Lys174) Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

ApplicationsWB

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous Tau when Acetyl occurs at Lys174

Immunogen DescSynthetic Acetyl peptide from human protein at AA range: 174

Target NameTau (Acetyl Lys174)

ConjugateUnconjugated

Other NamesMicrotubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)

Accession NoSwiss-Prot:P10636
NCBI Gene ID:4137

Uniprot P10636

Gene ID 4137;

Calculated MW50-85kD

Concentration1 mg/ml

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

StorageStore at -20˚C

Application Details

Western blotting: 1£º500-1£º2000

Western blot analysis of KB Hela lysate, antibody was diluted at 1000. Secondary antibody was diluted at 1:20000

If you have published an article using product HW181, please notify us so that we can cite your literature.

et al,Combination therapy with cilostazol, aripiprazole, and donepezil protects neuronal cells from β-amyloid neurotoxicity through synergistically enhanced SIRT1 expression. In Korean J Physiol Pharmacol on 2020 Jul 1 by Hye Jin Heo, So Youn Park, et al..PMID: 32587124 , (2020),
PMID: 32587124
et al,SIRT6-CBP-dependent nuclear Tau accumulation and its role in protein synthesis. In Cell Rep on 2021 Apr 27 by Miguel Portillo, Ekaterina Eremenko,et al..PMID:33910019 , (2021),
PMID: 33910019
et al,Glimepiride mitigates tauopathy and neuroinflammation in P301S transgenic mice: role of AKT/GSK3β signaling. In Inflammopharmacology on 2022 Oct by Mennatallah O Zaki, S El-Desouky, et al..PMID:35922737 , (2022),
PMID: 35922737

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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