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Location： Home > Methyl / Acetyl Antibodies > Histone H3(Di-mehtyl-Lys4) Antibody

Histone H3(Di-mehtyl-Lys4) Antibody#HW216

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Product NameHistone H3(Di-mehtyl-Lys4) Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationImmunogen affinity purified

ApplicationsWB, ICC, IHC, FC

Species ReactivityHu,Ms,Rt

Immunogen Descpeptide

ConjugateUnconjugated

Other NamesHIST1 cluster, H3J antibody
Histone gene cluster 1, H3 histone family, member E antibody
Histone gene cluster 1, H3G antibody
H3 histone family, member J antibody
HIST1 cluster, H3E antibody
HIST1 cluster, H3I antibody
Histone gene cluster 1, H3C antibody
FLJ92264 antibody
H3 histone family, member A antibody
H3 histone family, member B antibody
H3 histone family, member C antibody
H3 histone family, member D antibody
H3 histone family, member F antibody
H3 histone family, member H antibody
H3 histone family, member I antibody
H3 histone family, member K antibody
H3 histone family, member L antibody
H3 histone family, member T antibody
H3 histone, family 3A antibody
H3.1 antibody
H3.3A antibody
H3/a antibody
H3/b antibody
H3/c antibody
H3/d antibody
h3/f antibody
H3/h antibody
H3/i antibody
H3/j antibody
H3/k antibody
H3/l antibody
H3/t antibody
H31_HUMAN antibody
H3F1K antibody
H3F3 antibody
H3F3A antibody
H3FA antibody
H3FB antibody
H3FC antibody
H3FD antibody
H3FF antibody
H3FH antibody
H3FI antibody
H3FJ antibody
H3FK antibody
H3FL antibody
HIST1 cluster, H3A antibody
HIST1 cluster, H3B antibody
HIST1 cluster, H3C antibody
HIST1 cluster, H3D antibody
HIST1 cluster, H3F antibody
HIST1 cluster, H3G antibody
HIST1 cluster, H3H antibody
HIST1H3A antibody
HIST1H3B antibody
HIST1H3C antibody
HIST1H3D antibody
HIST1H3E antibody
HIST1H3F antibody
HIST1H3G antibody
HIST1H3H antibody
HIST1H3I antibody
HIST1H3J antibody
HIST3H3 antibody
Histone 1, H3a antibody
Histone 1, H3b antibody
Histone 1, H3c antibody
Histone 1, H3d antibody
Histone 1, H3e antibody
Histone 1, H3f antibody
Histone 1, H3g antibody
Histone 1, H3h antibody
Histone 1, H3i antibody
Histone 1, H3j antibody
histone 3, H3 antibody
histone cluster 1 H3 family member a antibody
histone cluster 1 H3 family member b antibody
histone cluster 1 H3 family member c antibody
histone cluster 1 H3 family member d antibody
histone cluster 1 H3 family member e antibody
histone cluster 1 H3 family member f antibody
histone cluster 1 H3 family member g antibody
histone cluster 1 H3 family member h antibody
histone cluster 1 H3 family member i antibody
histone cluster 1 H3 family member j antibody
Histone cluster 1, H3a antibody
Histone cluster 1, H3b antibody
Histone cluster 1, H3c antibody
Histone cluster 1, H3d antibody
Histone cluster 1, H3e antibody
Histone cluster 1, H3f antibody
Histone cluster 1, H3g antibody
Histone cluster 1, H3i antibody
Histone cluster 1, H3j antibody
Histone gene cluster 1, H3 histone family, member A antibody
Histone gene cluster 1, H3 histone family, member B antibody
Histone gene cluster 1, H3 histone family, member C antibody
Histone gene cluster 1, H3 histone family, member D antibody
Histone gene cluster 1, H3 histone family, member F antibody
Histone gene cluster 1, H3 histone family, member G antibody
Histone gene cluster 1, H3 histone family, member H antibody
Histone gene cluster 1, H3 histone family, member I antibody
Histone gene cluster 1, H3 histone family, member J antibody
Histone gene cluster 1, H3A antibody
Histone gene cluster 1, H3B antibody
Histone gene cluster 1, H3D antibody
Histone gene cluster 1, H3E antibody
Histone gene cluster 1, H3F antibody
Histone gene cluster 1, H3H antibody
Histone gene cluster 1, H3I antibody
Histone gene cluster 1, H3J antibody
Histone H 3 antibody
Histone H3.1 antibody
histone H3.1t antibody
Histone H3.2 antibody
Histone H3/a antibody
Histone H3/b antibody
Histone H3/c antibody
Histone H3/d antibody
Histone H3/f antibody
Histone H3/h antibody
Histone H3/i antibody
Histone H3/j antibody
Histone H3/k antibody
Histone H3/l antibody
Histone H3/m antibody
Histone H3/o antibody

Accession NoSwiss-Prot#:P68431

Uniprot P68431

Gene ID 8350;8351;8352;8353;8354;8355;8356;8357;8358;8968;

Calculated MW17kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1: 1,000



The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Methylation at Lys-5 (H3K4me), Lys-37 (H3K36me) and Lys-80 (H3K79me) are linked to gene activation. Methylation at Lys-5 (H3K4me) facilitates subsequent acetylation of H3 and H4. Methylation at Lys-80 (H3K79me) is associated with DNA double-strand break (DSB) responses and is a specific target for TP53BP1. Methylation at Lys-10 (H3K9me) and Lys-28 (H3K27me) are linked to gene repression. Methylation at Lys-10 (H3K9me) is a specific target for HP1 proteins (CBX1, CBX3 and CBX5) and prevents subsequent phosphorylation at Ser-11 (H3S10ph) and acetylation of H3 and H4. Methylation at Lys-5 (H3K4me) and Lys-80 (H3K79me) require preliminary monoubiquitination of H2B at 'Lys-120'. Methylation at Lys-10 (H3K9me) and Lys-28 (H3K27me) are enriched in inactive X chromosome chromatin.

If you have published an article using product HW216, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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