Product Detail
Product NameTNFAIP1 (Phospho-Ser280) Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
ApplicationsCustom antibody
Species ReactivityHu
Immunogen TypePeptide-KLH
Target NameTNFAIP1
ConjugateUnconjugated
Other NamesTumor necrosis factor, alpha-induced protein 1, endothelial; BACURD2
Accession Nouniprot:Q13829
Calculated MW36kDa
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Application Details
Western blotting: 1:500~1:1000
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
If you have published an article using product SAB037, please notify us so that we can cite your literature.
Yes
