Product Detail
Product NameDMAP1 (Phospho-Tyr246) Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was purified from rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
ApplicationsWB
Species ReactivityHMR
SpecificityDMAP1(Phospho-Tyr246) Antibody detects endogenous levels of DMAP1 only
when phosphorylated at Tyr246.
Immunogen DescA synthesized peptide derived from human DMAP1 around the phosphorylation site of Tyr246.
ConjugateUnconjugated
Other NamesDNA methyltransferase 1-associated protein 1; DNMAP1; DNMT1-associated protein 1; KIAA1425
Uniprot
Q9NPF5
Gene ID
55929
Sdspage MW53kDa
Concentration1 mg/ml
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM
NaCl,0.02% sodium azide and 50% glycerol.
StorageStore at --20˚C/1 year
Application Details
Western Blot: 1/500 - 1/2000
Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription.
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Yes
