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SUCLA2 (Phospho-Ser124) Antibody #SAB657

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Product Detail

Product NameSUCLA2 (Phospho-Ser124) Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationThe antibody was purified from rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

ApplicationsWB

Species ReactivityHuman,Mouse

SpecificitySUCLA2(Phospho-Ser124) Antibody detects endogenous levels of SUCLA2( only when phosphorylated at Ser124.

Immunogen DescA synthesized peptide derived from human SUCLA2 around the phosphorylation site of Ser124.

ConjugateUnconjugated

Other NamesSUCLA2,A-SCS,SCS-betaA

Uniprot Q9P2R7

Gene ID 8803

Sdspage MW50kDa

Concentration1 mg/ml

FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl,0.02% sodium azide.

StorageStore at --20˚C/1 year

Application Details
Western Blot: 1/500 - 1/2000
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA (PubMed:15877282). The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (By similarity).

If you have published an article using product SAB657, please notify us so that we can cite your literature.

et al,OXCT1 succinylation and activation by SUCLA2 promotes ketolysis and liver tumor growth. , (2025),
PMID: 39862868

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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