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GSK3b(Ab-9) Antibody #21002

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameGSK3b(Ab-9) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • ApplicationsWB IHC IF
  • Species ReactivityHuman, Mouse
  • SpecificityThe antibody detects endogenous level of total GSK3b protein, this antibodymay cross-react with the GSK-3a due to high sequence homology.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around aa.7~11 (T-T-S-F-A) derived from Human GSK3b.
  • Target NameGSK3b
  • Alternative Names    Factor A, GSK-3 beta, Protein kinase GSK-3-beta, kinase GSK-3 beta,
  • Accession No. Swiss-Prot: P49841
    NCBI Protein: NP_001139628.1
  • UniprotP49841
  • Gene ID2932;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Gut microbiota relieves inflammation in the substantia nigra of chronic Parkinson's disease by protecting the function of dopamine neurons. In Exp Ther Med on 2022 Jan by Tian Zhang, Tan Wang,et al..PMID:34934429, , (2022),
PMID: 34934429
The Therapeutic Effects of Seven Lycopodium Compounds on Cell Models of Alzheimer��s Disease. In J Alzheimers Dis on 2022 by Qian Guo, Qinfeng Cai ,et al..PMID:36189599, , (2022),
PMID: 36189599
Catalpol promotes the osteogenic differentiation of bone marrow mesenchymal stem cells via the Wnt/β-catenIn pathway. In Stem Cell Res Ther on 2019 Jan 22 by Zhu Y, Wang Y, et al.. PMID: 30670092, , (2019),
PMID: 30670092
GInkgolide B promotes osteoblast differentiation via activation of canonical Wnt signallIng and alleviates osteoporosis through a bone anabolic way. In J Cell Mol Med on 2019 Aug by Zhu B, Xue F, et al..PMID:31225702, , (2019),
PMID: 31225702
View All Published Papers The natural agent rhein induces β-catenin degradation and tumour growth arrest.In J Cell Mol Med. On 2018 Jan by Liu S, Wang J et al..PMID:29024409, , (2018),
PMID: 29024409
Melatonin ameliorates Aβ1 42 induced Alzheimer's cognitive deficits in mouse model.In J Pharm Pharmacol.On 2018 Jan by Gong YH, Hua N et al..PMID: 28994117 , , (2018),
PMID: 28994117
Risperidone ameliorated Aβ1-42-induced cognitive and hippocampal synaptic impairments in mice.In Behav Brain Res on 2017 Mar 30 by Lingzhi Wu , Xiaowen Feng,et al..PMID: 28093254, , (2017),
PMID: 28093254
Glutathione-s-transferase A 4 (GSTA4) Suppresses Tumor Growth and Metastasis of Human Hepatocellular Carcinoma by Targeting AKT Pathway.In Am J Transl Res on 2017 Feb 15 by Chang Jun Liu, Jin Hui Yang,et al..PMID: 28337261, , (2017),
PMID: 28337261
IGF-1-mediated PKM2/β-catenin/miR-152 Regulatory Circuit in Breast Cancer.In Sci Rep on 2017 Nov 21 by Yi-Yang Wen, Wei-Tao Liu,et al..PMID: 29162853, , (2017),
PMID: 29162853
Overexpression of astrocyte-elevated gene-1 is associated with ovarian cancer development and progression.In Mol Med Rep on 2015 Apr by Bo Zhou , Jue Yang et al..PMID:25483832, , (2015),
PMID: 25483832
Fumosorinone, a Novel PTP1B Inhibitor, Activates Insulin Signaling in Insulin-Resistance HepG2 Cells and Shows Anti-Diabetic Effect in Diabetic KKAy Mice .In Toxicol Appl Pharmacol On 2015 May 15 by Zhi-Qin Liu , Ting Liu et al..PMID: 25796170 , , (2015),
PMID: 25796170
Erythropoietin attenuates Alzheimer-like memory impairments and pathological changes induced by amyloid β42 in mice.In Brain Res on 2015 Aug 27 by Yi-Pei Li, Guo-Jun Yang et al..PMID:26049128, , (2015),
PMID: 26049128
SNAILs promote G1 phase in selected cancer cells.In Int J Oncol on 2015 Nov by Ya-Lan Wu , Jian-Xin Xue et al ..PMID:26352801, , (2015),
PMID: 26352801
Perfluorooctanoic Acid Exposure for 28 Days Affects Glucose Homeostasis and Induces Insulin Hypersensitivity in Mice .In Sci Rep on 2015 Jun 12 by Shengmin Yan, Hongxia Zhang et al..PMID: 26066376 , , (2015),
PMID: 26066376
Analysis of β-N-methylamino-l-alanine (L-BMAA) neurotoxicity in rat cerebellum.In Neurotoxicology on 2015 May by Emma Mu?oz-Sez , Estefana de Munck Garca et al..PMID:25898785, , (2015),
PMID: 25898785
Perfluorooctanoic Acid Exposure for 28 Days Affects Glucose Homeostasis and Induces Insulin Hypersensitivity in Mice .In Sci Rep on 2015 Jun 12 by Shengmin Yan, Hongxia Zhang et al..PMID: 26066376 , , (2015),
PMID: 26066376
Lithium chloride decreases proliferation and migration of C6 glioma cells harboring isocitrate dehydrogenase 2 mutant via GSK-3β.In Mol Biol Rep on 2014 Jun by Yuejun Fu , Yali Zheng et al..PMID:24549719, , (2014),
PMID: 24549719
GSK3 protein positively regulates type I insulin-like growth factor receptor through forkhead transcription factors FOXO1/3/4.In J Biol Chem on 2014 Sep 5 by Xiaodong Huo , Shu Liu et al..PMID:25053419, , (2014),
PMID: 25053419
A β1/2 Adrenergic Receptor-Sensitive Intracellular Signaling Pathway Modulates CCL2 Production in Cultured Spinal Astrocytes.In J Cell Physiol on 2014 Mar by Norimitsu Morioka , Hiromi Abe et al..PMID:24037783, , (2014),
PMID: 24037783
Phosphoproteome analysis reveals an important role for glycogen synthase kinase-3 in perfluorododecanoic acid-induced rat liver toxicity. In Toxicol Lett on 2013 Mar 27 by Hongxia Zhang, Junjie Hou, et al..PMID: 23353032, , (2013),
PMID: 23353032
Concerted suppression of STAT3 and GSK3β is involved in growth inhibition of non-small cell lung cancer by xanthatin. In PLoS One on 2013 Nov 28 by Li Tao, Fangtian Fan, et al..PMID: 24312384 , , (2013),
PMID: 24312384
Signal regulatory protein α negatively regulates mast-cell activation following FcεRI aggregation. In Eur J Immunol on 2013 Jun by Yu-fei Pan, Li-wei Dong, et al..PMID: 23504624, , (2013),
PMID: 23504624
The midregion, nuclear localization sequence, and C terminus of PTHrP regulate skeletal development, hematopoiesis, and survival in mice.In FASEB J on 2010 Jun by Toribio RE, Brown HA,et al..PMID:20145205, , (2010),
PMID: 20145205
Protective effects of lithium treatment for spatial memory deficits induced by tau hyperphosphorylation in splenectomized rats.In Clin Exp Pharmacol Physiol on 2010 Oct by Tan WF, Cao XZ,et al..PMID:20659131, , (2010),
PMID: 20659131
Please let us know if you have published research using #21002 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep