• Product NamePPP1R13B Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total PPP1R13B protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human Apoptosis-stimulating of p53 protein 1
• Target NamePPP1R13B
• Alternative Names    PPP1R13B; KIAA0771; p53BP2-like; p85
• Accession No. Swiss-Prot#: Q96KQ4
  NCBI Gene ID: 23368
  Gene Accssion: NP_056131.1
• UniprotQ96KQ4
• Gene ID23368;
• Concentration 2mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

The protein plays a central role in regulation of apoptosis via its interaction with p53/TP53.Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.It contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins.

• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #36764 at dilution 1/35.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting