• Product NameICOSLG Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ICOSLG protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human inducible T-cell co-stimulator ligand
• Target NameICOSLG
• Alternative Names    B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L
• Accession No. Swiss-Prot#: O75144
  NCBI Gene ID: 23308
  Gene Accssion: NP_056074/O75144
• UniprotO75144
• Gene ID23308;
• SDS-PAGE MW 33kd
• Concentration 1.3mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  

ICOS ligand?is a?protein?that in humans is encoded by the?ICOSLG?gene. ICOSLG has also been designated as CD275 (cluster of differentiation 275). Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.

• Gel: 6%SDS-PAGE
  Lysates (from left to right): Human fetal brain and human lymphoma tissue
  Amount of lysate: 80ug per lane
  Primary antibody: 1/100 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 10 minutes

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting