• Product NameFOSB Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total FOSB protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human FBJ murine osteosarcoma viral oncogene homolog B
• Target NameFOSB
• Alternative Names    AP-1; G0S3; GOS3; GOSB
• Accession No. Swiss-Prot#: P53539
  NCBI Gene ID: 2354
  Gene Accssion: NP_006723/P53539
• UniprotP53539
• Gene ID2354;
• SDS-PAGE MW 36kd
• Concentration 1.3mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:50-1:200

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Gel: 8%SDS-PAGE
  Lysates (from left to right): Human kidney cancer and lung cancer tissue, human placenta tissue
  Amount of lysate: 40ug per lane
  Primary antibody: 1/200 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 10 minutes
• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #36855 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting