• Product NameING1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total ING1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the N terminal of human inhibitor of growth family, member 1
• Target NameING1
• Alternative Names    p33; p47; p33ING1; p24ING1c; p33ING1b; p47ING1a
• Accession No. Swiss-Prot#: Q9UK53
  NCBI Gene ID: 3621
  Gene Accssion: NP_005528
• UniprotQ9UK53
• Gene ID3621;
• SDS-PAGE MW 47kd
• Concentration 1.6mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
  

This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

• Gel: 8%SDS-PAGE
  Lysates (from left to right): Hela cell and mouse brain tissue, Jurkat and Raw264.7 cell
  Amount of lysate: 40ug per lane
  Primary antibody: 1/267 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 1 second

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting