• Product NameLRIG1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total LRIG1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human leucine-rich repeats and immunoglobulin-like domains 1
• Target NameLRIG1
• Alternative Names    LIG1; LIG-1
• Accession No. Swiss-Prot#: Q96JA1
  NCBI Gene ID: 26018
  Gene Accssion: NP_056356
• UniprotQ96JA1
• Gene ID26018;
• Concentration 3.8mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:50-1:200

Leucine-rich repeats and immunoglobulin-like domains protein 1?is a?protein?that in humans is encoded by the?LRIG1?gene.?It encodes a?transmembrane protein?that has been shown to interact with receptor tyrosine kinases of the?EGFR-family?,?MET?and?RET. Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.

• Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using #36954 at dilution 1/120.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting