• Product NameMC2R Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total MC2R protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the N terminal of human Melanocortin 2 receptor (adrenocorticotropic hormone)
• Target NameMC2R
• Alternative Names    ACTHR
• Accession No. Swiss-Prot#: Q01718
  NCBI Gene ID: 4158
  Gene Accssion: NP_000520
• UniprotQ01718
• Gene ID4158;
• SDS-PAGE MW 34kd
• Concentration 2.1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:1000-1:5000
  

MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.

• Gel: 10%SDS-PAGE
  Lysates (from left to right): Human fetal kidney tissue
  Amount of lysate: 40ug per lane
  Primary antibody: 1/1400 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 2 minutes

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting