• Product NameSOCS7 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SOCS7 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the N terminal of human suppressor of cytokine signaling 7
• Target NameSOCS7
• Alternative Names    NAP4; NCKAP4
• Accession No. Swiss-Prot#: O14512
  NCBI Gene ID: 30837
  Gene Accssion: NP_055413
• UniprotO14512
• Gene ID30837;
• Concentration 1.1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:50-1:200

The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.

• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #37039 at dilution 1/30.
• Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using #37039 at dilution 1/30.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting