• Product NameS1PR1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total S1PR1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human Sphingosine-1-phosphate receptor 1
• Target NameS1PR1
• Alternative Names    EDG1; S1P1; CD363; ECGF1; EDG-1; CHEDG1; D1S3362
• Accession No. Swiss-Prot#: P21453
  NCBI Gene ID: 1901
  Gene Accssion: NP_001391
• UniprotP21453
• Gene ID1901;
• SDS-PAGE MW 43kd
• Concentration 1.4mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
  

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.

• Gel: 10%SDS-PAGE
  Lysates (from left to right): Mouse brain tissue
  Amount of lysate: 40ug per lane
  Primary antibody: 1/700 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 10 seconds

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting