• Product NamePDE6C Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total PDE6C protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the N terminal of human phosphodiesterase 6C, cGMP-specific, cone, alpha prime
• Target NamePDE6C
• Alternative Names    COD4; ACHM5; PDEA2
• Accession No. Swiss-Prot#: P51160
  NCBI Gene ID: 5146
  Gene Accssion: NP_006195
• UniprotP51160
• Gene ID5146;
• SDS-PAGE MW 99kd
• Concentration 2.8mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
  

Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' is an enzyme that in humans is encoded by the PDE6C gene. This gene encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4).

• Gel: 6%SDS-PAGE
  Lysate: 40ug A172 cell
  Primary antibody: 1/1400 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 10 seconds

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting