• Product NameSPR Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SPR protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
• Target NameSPR
• Alternative Names    SDR38C1
• Accession No. Swiss-Prot#: P35270
  NCBI Gene ID: 6697
  Gene Accssion: NP_003115
• UniprotP35270
• Gene ID6697;
• SDS-PAGE MW 28kd
• Concentration 2.6mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
  Immunohistochemistry: 1:50-1:200

This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

• Gel: 10%SDS-PAGE
  Lysates (from left to right): Human chromaffin cell tumor tissue and lovo cell
  Amount of lysate: 40ug per lane
  Primary antibody: 1/1500 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 10 seconds
• Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #37391 at dilution 1/40.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting