Cleft lip and palate transmembrane protein 1-like protein?(CLPTM1-like protein), also known as?cisplatin resistance-related protein 9?(CRR9p), is a?protein?that in humans is encoded by the?CLPTM1L?gene.?CRR9p is associated with?cisplatin-induced?apoptosis.?CLPTM1L, which lies within a cancer susceptibility locus on chromosome 5 (5p15.33), has been found to be commonly over-expressed in lung tumors and to confer resistance to apoptosis caused by genotoxic agents in association with up-regulation of the anti-apoptotic protein, Bcl-xL.
