• Product NameIL17RB Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total IL17RB protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human interleukin 17 receptor B
• Target NameIL17RB
• Alternative Names    CRL4; EVI27; IL17BR; IL17RH1
• Accession No. Swiss-Prot#: Q9NRM6
  NCBI Gene ID: 55540
  Gene Accssion: NP_061195
• UniprotQ9NRM6
• Gene ID55540;
• Concentration 2.8mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:50-1:200

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.

• Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37649 at dilution 1/40.
• Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #37649 at dilution 1/40.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting