• Product NameMAP3K11 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total MAP3K11 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human mitogen-activated protein kinase kinase kinase 11
• Target NameMAP3K11
• Alternative Names    MLK3; PTK1; SPRK; MLK-3; MEKK11
• Accession No. Swiss-Prot#: Q16584
  NCBI Gene ID: 4296
  Gene Accssion: NP_002410
• UniprotQ16584
• Gene ID4296;
• SDS-PAGE MW 93kd
• Concentration 0.8mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
  Immunohistochemistry: 1:50-1:100

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.?

• Gel: 6%SDS-PAGE Lysate: 40 μg Lane: LO2 and PC-3 cell lysates Primary antibody: MAP3K11 Antibody at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 5 minutes
• The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using MAP3K11 Antibody at dilution 1/30. (Original magnification: ×200)
• The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using MAP3K11 Antibody at dilution 1/30. (Original magnification: ×200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting