• Product NameNLRP12 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total NLRP12 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human NLR family, pyrin domain containing 12
• Target NameNLRP12
• Alternative Names    RNO; PAN6; RNO2; FCAS2; NALP12; PYPAF7; CLR19.3
• Accession No. Swiss-Prot#: P59046
  NCBI Gene ID: 91662
  Gene Accssion: NP_653288
• UniprotP59046
• Gene ID91662;
• Concentration 1.9mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

• Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #37750 at dilution 1/30.
• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #37750 at dilution 1/30.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting