• Product NameSLC22A12 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SLC22A12 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide of human SLC22A12
• Target NameSLC22A12
• Alternative Names    RST; OAT4L; URAT1
• Accession No. Swiss-Prot#: Q96S37
  NCBI Gene ID: 116085
  Gene Accssion: NP_653186
• UniprotQ96S37
• Gene ID116085;
• SDS-PAGE MW 60kd
• Concentration 0.6 mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• WB 1:500-1:2000;
  IHC 1:50-1:200

The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants.

• Gel: 8%SDS-PAGE Lysate: 40 ug Lane 1-2: Hela and HepG2 cell lysates Primary antibody: (SLC22A12 Antibody) at dilution 1/700 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute
• The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (SLC22A12 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
• The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using (SLC22A12 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting