• Product NamePAPPA Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total PAPPA protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human pregnancy-associated plasma protein A, pappalysin 1
• Target NamePAPPA
• Alternative Names    PAPA; DIPLA1; PAPP-A; PAPPA1; ASBABP2; IGFBP-4ase
• Accession No. Swiss-Prot#: Q13219
  NCBI Gene ID: 5069
  Gene Accssion: NP_002572
• UniprotQ13219
• Gene ID5069;
• Concentration 3.1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:50-1:200

This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.

• Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using #37794 at dilution 1/50.
• Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37794 at dilution 1/50.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting