• Product NamePLXNA4 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total PLXNA4 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human plexin A4
• Target NamePLXNA4
• Alternative Names    PLEXA4; PLXNA4A; PLXNA4B; FAYV2820; PRO34003
• Accession No. Swiss-Prot#: Q9HCM2
  NCBI Gene ID: 91584
  Gene Accssion: NP_001099013/Q9HCM2
• UniprotQ9HCM2
• Gene ID91584;
• Concentration 3mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:50-1:200

Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

• Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using #37835 at dilution 1/50.
• Immunohistochemical analysis of paraffin-embedded Human brain tissue using #37835 at dilution 1/50.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting