• Product NameDYN1 (Phospho-Ser778) Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of DYN1 only when phosphorylated at serine 778.
• Immunogen Typepeptide
• Immunogen DescriptionPeptide sequence around phosphorylation site of serine 778 (T-S-S(p)-P-T) derived from Human DYN1.
• Target NameDYN1
• ModificationPhospho
• Alternative Names    B-dynamin; D100; DNM; DNM1; Dynamin BREDNM19; Dynamin; brain; dynamin-1
• Accession No. Swiss-Prot#:Q05193;
  NCBI Gene#:1759
• UniprotQ05193
• Gene ID1759;
• SDS-PAGE MW 100kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.

• Western blot analysis of extracts from Mouse brain cells, using DYN1 (Phospho-Ser778) antibody #12136. The lane on the right is treated with the synthesized peptide.
• Western blot analysis of extracts from HepG2 cells (Lane 2), using DYN1 (Phospho-Ser778) Antibody #12136. The lane on the left is treated with synthesized peptide.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting