• Product NameIL17A antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman
• SpecificityThe antibody detects endogenous level of total IL17A protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant fusion protein of human IL17A (NP_002181.1).
• Target NameIL17A
• Alternative Names    IL17A;CTLA-8;CTLA8;IL-17;IL-17A;IL17
• Accession No. Uniprot:Q16552
  GeneID:3605
• UniprotQ16552
• Gene ID3605
• SDS-PAGE MW 18-25kDa
• Concentration 1.0mg/ml
• Formulation PBS with 0.05% proclin300, 50% glycerol, pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:1000
  

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

• Western blot analysis of various lysates, using IL17A at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10000

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting