• Product NameEDNRB antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB
• Species ReactivityHuman,Mouse
• SpecificityThe antibody detects endogenous level of total EDNRB protein.
• Immunogen TypePeptide
• Immunogen DescriptionA synthetic peptide of human EDNRB .
• Target NameEDNRB
• Alternative Names    ETB;ET-B;ETBR;ETRB;HSCR;WS4A;ABCDS;ET-BR;HSCR2;
• Accession No. Swiss-Prot#: P24530
  NCBI Gene ID: 1910
• UniprotP24530
• Gene ID1910;
• SDS-PAGE MW 50kd
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Western blot analysis of extracts of various cell lines, using EDNRB at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting