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IGF-1R(Phospho-Tyr1165/Tyr1166) Antibody #11088

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameIGF-1R(Phospho-Tyr1165/Tyr1166) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB, IHC
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of IGF-1R only when phosphorylated at tyrosine 1165/tyrosine1166.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of tyrosine 1165/tyrosine 1166 (T-D-Y(p)-Y(p)-R-K) derived from Human IGF-1R .
  • Target NameIGF-1R
  • ModificationPhospho
  • Alternative Names    Insulin-like growth factor I receptor; CD221; IGF1R; kinase IGF1R;
  • Accession No. Swiss-Prot: P08069
    NCBI Protein: NP_000866.1
  • UniprotP08069
  • Gene ID3480;
  • Concentration 1.0mg/ml
  • Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Tau-Induced Ca2+/Calmodulin-Dependent Protein Kinase-IV Activation Aggravates Nuclear Tau Hyperphosphorylation .In Neurosci Bull. On 2018 Apr by Wei YP, Ye JW et al..PMID: 28646348, , (2019),
PMID: 28646348
Tau-Induced Ca2+/Calmodulin-Dependent Protein Kinase-IV Activation Aggravates Nuclear Tau Hyperphosphorylation .In Neurosci Bull. On 2018 Apr by Wei YP, Ye JW et al..PMID: 28646348, , (2018),
PMID: 28646348
H 2 O 2 Attenuates IGF-1R Tyrosine Phosphorylation and Its Survival Signaling Properties in Neuronal Cells via NR2B Containing NMDA Receptor.In Oncotarget on 2017 Jun 27 by Zhiwen Zeng, Dejun Wang,et al..PMID: 29029433, , (2017),
PMID: 29029433
Glutamate Attenuates IGF-1 Receptor Tyrosine Phosphorylation in Mouse Brain: Possible Significance in Ischemic Brain Damage.In Neurosci Res on 2012 Dec by Chengming Sun, Qian Meng,et al..PMID:23085572, , (2012),
PMID: 23085572
Please let us know if you have published research using #11088 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep