• Product NameMTA3 antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total MTA3 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant protein of human MTA3.
• Target NameMTA3
• Accession No. Swiss-Prot#: Q9BTC8
  NCBI Gene ID: 57504
• UniprotQ9BTC8
• Gene ID57504;
• SDS-PAGE MW 67kd
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200

Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.

• Immunohistochemistry of paraffin-embedded rat kidney using MTA3 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human tonsil using MTA3 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human vermiform appendix using MTA3 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded mouse lung using MTA3 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded mouse liver using MTA3 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded mouse testis using MTA3 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded mouse spleen using MTA3 at dilution of 1:100 (40x lens).
• Western blot analysis of extracts of various cell lines, using MTA3 at 1:1000 dilution.
• Immunohistochemistry of paraffin-embedded rat heart using MTA3 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human lung cancer using MTA3 at dilution of 1:100 (40x lens).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting