• Product NameTSHR antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total TSHR protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant protein of human TSHR.
• Target NameTSHR
• Alternative Names    LGR3; CHNG1; hTSHR-I;
• Accession No. Swiss-Prot#: P16473
  NCBI Gene ID: 7253
• UniprotP16473
• Gene ID7253;
• SDS-PAGE MW 86kd
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

• Immunohistochemistry of paraffin-embedded rat brain using TSHR at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded mouse brain using TSHR at dilution of 1:100 (40x lens).
• Western blot analysis of extracts of various cell lines, using TSHR at 1:1000 dilution.
• Immunohistochemistry of paraffin-embedded rat brain using TSHR at dilution of 1:100 (40x lens).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting