• Product NameSCAP Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SCAP protein.
• Immunogen TypeProtein
• Immunogen DescriptionFusion protein corresponding to a region derived from internal residues of human SREBF chaperone
• Target NameSCAP
• Accession No. Swiss-Prot:Q12770
  Gene Accssion:BC020987
• UniprotQ12770
• Gene ID22937;
• Concentration 1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry:1:25-1:100

This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.

• Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #40093 at dilution 1/20.
• Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #40093 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting