• Product NameSEMA4C Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SEMA4C protein.
• Immunogen TypeProtein
• Immunogen DescriptionFusion protein corresponding to residues near the C terminal of human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
• Target NameSEMA4C
• Alternative Names    SEMAF; SEMAI; SEMACL1; M-SEMA-F
• Accession No. Swiss-Prot:Q9C0C4
  Gene Accssion:BC109104
• UniprotQ9C0C4
• Gene ID54910;
• Concentration 1.1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry:1:25-1:100

Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.

• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #40099 at dilution 1/20.
• Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #40099 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting