• Product NameSTXBP4 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total STXBP4 protein.
• Immunogen TypeProtein
• Immunogen DescriptionFusion protein corresponding to residues near the C terminal of human syntaxin binding protein 4
• Target NameSTXBP4
• Alternative Names    Synip
• Accession No. Swiss-Prot:Q08AL9
  Gene Accssion:BC125116
• UniprotQ08AL9
• Concentration 1.9mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry:1:25-1:100

Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.

• Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #40130 at dilution 1/35.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting