• Product NameCERS3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total CERS3 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human ceramide synthase 3
• Target NameCERS3
• Alternative Names    ARCI9; LASS3
• Accession No. Swiss-Prot:Q8IU89
  Gene Accssion:NP_849164
• UniprotQ8IU89
• Gene ID204219;
• SDS-PAGE MW 46KD
• Concentration 1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000

LASS3 is a 383 amino acid membrane protein almost exclusively expressed in testis, suggesting that LASS3 plays an important role in proper testis function. It is also weakly expressed in skin. A transcriptional variant of LASS3 cDNA exists and can result in the production of a 419 amino acid protein (LASS3-long). LASS3 overproduction raises the level of several ceramide species, including C18:0- and C24:0-ceramides.

• Gel: 8%SDS-PAGE
  Lysate: 40ug TM4 cellPrimary antibody: 1/200 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 3 minutes

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting