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Tau(Phospho-Thr181) Antibody #11107

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameTau(Phospho-Thr181) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of Tau only when phosphorylated at threonine 181.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of threonine 181 (P-K-T(p)-P-P) derived from Human Tau.
  • Target NameTau
  • ModificationPhospho
  • Alternative Names    MAPT; MTAPT; MTBT1; Neurofibrillary tangle protein; PHF-tau
  • Accession No. Swiss-Prot: P10636
    NCBI Protein: NP _001116538.1
  • UniprotP10636
  • Gene ID4137;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Differences in Tau Seeding in Newborn and Adult Wild-Type Mice. In Int J Mol Sci on 2022 Apr 26 by Isidro Ferrer, Pol Andr��s-Benito,et al..PMID:35563179, , (2022),
PMID: 35563179
Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission. In Cell Stem Cell on 2020 Mar 5 by Jie Zheng, Hong-Lian Li,et al..PMID:31978364, , (2020),
PMID: 31978364
CHP2 Promotes Cell Proliferation in Breast Cancer via Suppression of FOXO3a.In Mol Cancer Res.On 2018 Oct by Zhao X, Xie T et al..PMID: 29967111, , (2019),
PMID: 29967111
The Natural Compound Myricetin Effectively Represses the Malignant Progression of Prostate Cancer by Inhibiting PIM1 and Disrupting the PIM1/CXCR4 Interaction .In Cell Physiol Biochem. On 2018 by Ye C, Zhang C et al..PMID: 30045021, , (2018),
PMID: 30045021
View All Published Papers Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells.In Front Neurosci on 2017 Jan 31 by Xiaping He , Zhenhui Li,et al..PMID: 28197064, , (2017),
PMID: 28197064
Ribosylation triggering A lzheimer's disease-like T au hyperphosphorylation via activation of C a MKII.In Aging Cell on 2015 Oct by Yan Wei, Chanshuai Han et al..PMID:26095350, , (2015),
PMID: 26095350
Role of PrPC Expression in Tau Protein Levels and Phosphorylation in Alzheimers Disease Evolution.In Mol Neurobiol on 2015 by C Vergara, L Ord?ez-Gutirrez et al..PMID: 24965601, , (2015),
PMID: 24965601
Role of PrPC Expression in Tau Protein Levels and Phosphorylation in Alzheimers Disease Evolution.In Mol Neurobiol on 2015 by C Vergara, L Ord?ez-Gutirrez et al..PMID: 24965601, , (2015),
PMID: 24965601
Two widely used RSK inhibitors, BI-D1870 and SL0101, alter mTORC1 signaling in a RSK-independent manner. In Cell Signal on 2015 Aug by Martn Roff, Fernanda C Lupinacci,et al..PMID:25889895, , (2015),
PMID: 25889895
A Novel Mechanism for Endogenous Formaldehyde Elevation in SAMP8 Mouse .In J Alzheimers Dis On 2014 by Min Qiang , Rong Xiao et al..PMID:24583407, , (2014),
PMID: 24583407
Alzheimer's Disease and Methanol Toxicity (Part 1): Chronic Methanol Feeding Led to Memory Impairments and Tau Hyperphosphorylation in Mice. In J Alzheimers Dis on 2014 by Meifeng Yang, Jing Lu,et al..PMID:24787915, , (2014),
PMID: 24787915
A Novel Mechanism for Endogenous Formaldehyde Elevation in SAMP8 Mouse .In J Alzheimers Dis On 2014 by Min Qiang , Rong Xiao et al..PMID:24583407, , (2014),
PMID: 24583407
Cellular prion protein modulates β-amyloid deposition in aged APP/PS1 transgenic mice. In Neurobiol Aging on 2013 Dec by Juan Mara Torres, Rosalina Gavn, et al..PMID: 23831375, , (2013),
PMID: 23831375
Cellular prion protein modulates β-amyloid deposition in aged APP/PS1 transgenic mice. In Neurobiol Aging on 2013 Dec by Juan Mara Torres, Rosalina Gavn, et al..PMID: 23831375, , (2013),
PMID: 23831375
Please let us know if you have published research using #11107 so that we can cite your reference.

Customer Reviews and Rankings

Anonymous user 05-30-2021 19:42:19

Could you provide Catalog #11107 and #11724 of MSDS files for user. We appreciate your kindly help

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep