• Product NameUBXN1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsWB, IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total UBXN1 protein.
• Immunogen Typeprotein
• Immunogen DescriptionFull length fusion protein
• Target NameUBXN1
• Alternative Names    2B28; SAKS1; UBXD10
• Accession No. Swiss-Prot#:Q04323
  NCBI Gene ID:51035
  Gene Accssion:BC001372
• UniprotQ04323
• Gene ID51035;
• Calculated MW 33 kDa
• Concentration 1.2mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20C

• Western blotting:1:500-2000
  Immunofluorescence:1: 40-200

Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.

• The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 47231(UBXN1 Antibody) at dilution 1/35. (Original magnification: ?00)
• The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 47231(UBXN1 Antibody) at dilution 1/35. (Original magnification: ?00)
• Gel: 12%SDS-PAGE
  Lysate: 40 μg, Lane 1-3: Mouse brain tissue, Hela and HEPG2 cell lysates
  Primary antibody:UBXN1 Antibody at dilution 1/500
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
  Exposure time: 5 seconds

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting