• Product NameUACA Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total UACA protein.
• Immunogen TypeProtein
• Immunogen DescriptionFusion protein of human uveal autoantigen with coiled-coil domains and ankyrin repeats
• Target NameUACA
• Alternative Names    NUCLING
• Accession No. Swiss-Prot:Q9BZF9
  Gene Accssion:BC113407
• UniprotQ9BZF9
• Gene ID55075;
• Concentration 2.7mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry:1:30-1:150

Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).

• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #40351 at dilution 1/45.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting