• Product NameTRADD antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationPurified by antigen-affinity chromatography.
• ApplicationsWB IHC IF
• Species ReactivityHu Ms
• Immunogen TypePeptide
• Immunogen DescriptionA synthesized peptide derived from human TRADD
• Target NameTRADD
• Accession No. NCBI Gene ID: 8717
  NCBI mRNA#: NM_003789
  NCBI Protein#: NP_003780
• UniprotQ15628
• Gene ID8717;
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.

• Predicted MW: 34kd
  Western blotting: 1:500-1:3000
  Immunohistochemistry: 1:50-1:200

The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq]

• Western blot analysis on COS7 and HuvEc cell lysate using TRADD Antibody

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting