Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.
FanC is the main component of the K99 fimbriae.
"The penultimate tyrosine residue of the K99 fibrillar subunit is essential for stability of the protein and its interaction with the periplasmic carrier protein."
Simons B.L., Rathman P., Maij C.R., Oudega B., de Graaf F.K.
FEMS Microbiol. Lett. 55:107-112(1990)
Research Topic:Others