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Cleaved-Caspase-3 p17 (D175) Polyclonal Antibody #40500

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameCleaved-Caspase-3 p17 (D175) Polyclonal Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • ApplicationsWB IHC IF
  • Species ReactivityHu Ms Rt
  • SpecificityCleaved-Caspase-3 p17 (D175) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-3 p17 protein resulting from cleavage adjacent to D175.
  • Immunogen DescriptionSynthesized peptide derived from the Internal region of human Caspase-3 p17.
  • Target NameCleaved-Caspase-3 p17
  • Alternative Names    CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1
  • Accession No. Swiss-Prot: P42574
    NCBI Gene ID: 836
  • UniprotP42574
  • Gene ID836;
  • SDS-PAGE MW 20kd
  • Concentration 1mg/ml
  • Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Storage Store at -20˚C/1 year
Application Details

Published Papers

BDNF-TrkB/proBDNF-p75NTR pathway regulation by lipid emulsion rescues bupivacaine-induced central neurotoxicity in ratsInSci RepOn2023;byDanting Jia,#1?Fang Wang et al..PMID:?37884604, , (2023),
PMID: 37884604
Neuronal SH2B1 attenuates apoptosis in an MPTP mouse model of Parkinson's disease via promoting PLIN4 degradation. In Redox Biol on 2022 Jun by Xiaojuan Han, Yuan Liu, et al..PMID: 35390677, , (2022),
PMID: 35390677
Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling.Incell Death Dis. On 2018 Feb 13 by Wang Z, Ma L et al..PMID:29440765, , (2018),
PMID: 29440765
Please let us know if you have published research using #40500 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep