• Product NameCorticotropin-releasing factor receptor 2
• Brief DescriptionRecombinant Protein
• Host SpeciesE.coli
• PurificationGreater than 90% by SDS-PAGE
• Species ReactivityRat
• Immunogen Description1-108AA
• Alternative Names    Crf2r,Corticotropin-releasing hormone receptor 2,CRH-R-2
• Accession No. P47866
  Gene name:Crhr2
• UniprotP47866
• Gene ID64680;
• Calculated MW 11.88
• Tag Info His
• Formulation 50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
• Storage Store at -20C. (Avoid repeated freezing and thawing.)
  Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.

G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.

Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting