• Product NameBeta-secretase 2
• Brief DescriptionRecombinant Protein
• Host SpeciesE.coli
• PurificationGreater than 90% by SDS-PAGE
• Species ReactivityHuman
• Immunogen DescriptionRecombinant protein
• Alternative Names    CDA13,UNQ418/PRO852,AEPLC,ALP56,ASP21,Aspartic-like protease 56 kDa,Aspartyl protease 1,Beta-site amyloid precursor protein cleaving enzyme 2,Down region aspartic protease,Memapsin-1,Membrane-associated aspartic protease 1,Theta-secretase,ASP1,Beta-site APP cleaving enzyme 2,DRAP
• Accession No. Q9Y5Z0
  Gene name:BACE2
• UniprotQ9Y5Z0
• Gene ID25825;
• Tag Info His
• Formulation 50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
• Storage Store at -20C. (Avoid repeated freezing and thawing.)
  Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.

Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting