• Product NameZiprasidone hydrochloride
• Brief DescriptionInhibitors
• Purification99.07%
• Biological ActivityZiprasidone (hydrochloride) is a combined?5-HT (serotonin)?and?dopamine receptor?antagonist which exhibits potent effects of antipsychotic activity.
• Target Name5-HT Receptor antagonist; Adrenergic Receptor antagonist; Dopamine Receptor antagonist; Histamine Receptor antagonist; Norepinephrine antagonist
• CAS No. 122883-93-6
• Calculated MW 449.4
• Formulation C21H22CL2N4OS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:Cl.ClC1=C(CCN2CCN(CC2)C2=NSC3=CC=CC=C23)C=C2CC(=O)NC2=C1
  Pathways:GPCR/G Protein; Neuroscience; Immunology/Inflammation
  Receptor:5-HT transporter; 5-HT1A; 5-HT1B; 5-HT1D; 5-HT2A; 5-HT2C; 5-HT6; 5-HT7; α1A-adrenergic receptor; α2A-adrenergic receptor; D1; D2; D3; H1 receptor; norepinephrine transporter (NET)
  Boling pt:554.8C
  Melting pt:
  Solubility:DMSO: 90 mg/mL (200.26 mM)
  Appearance:Dusty Pink Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Seeger TF, et al. J Pharmacol Exp Ther. 1995 Oct;275(1):101-13.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting