• Product NameMiltefosine
• Brief DescriptionInhibitors
• Purification99.45%
• Biological ActivityMiltefosine is used for the treatment of visceral and cutaneous leishmaniasis, and is undergoing clinical trials for this use in several other countries. Several medical agents have some efficacy against visceral or cutaneous leishmaniasis, however a 2005 survey concluded that miltefosine is the only effective oral treatment for both forms of leishmaniasis.
• Target NamePKC inhibitor
• CAS No. 58066-85-6
• Calculated MW 407.58
• Formulation C21H46NO4P
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CCCCCCCCCCCCCCCCOP(O)(=O)OCC[N+](C)(C)C
  Pathways:Cytoskeletal Signaling
  Receptor:PKC
  Boling pt:486C?
  Melting pt:149-153C
  Solubility:Ethanol: 82 mg/mL (201.19 mM); Water: 82 mg/mL (201.19 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Uberall F, et al. Y Res, 1991, 51(3), 807-812.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting