• Product NameDoxapram hydrochloride monohydrate
• Brief DescriptionInhibitors
• Purification99.74%
• Biological ActivityDoxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
• Target NamePotassium Channel inhibitor
• CAS No. 7081-53-0
• Calculated MW 432.99
• Formulation C24H33ClN2O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Respiratory system
  SMILES:O.Cl.CCN1CC(CCN2CCOCC2)C(C1=O)(C1=CC=CC=C1)C1=CC=CC=C1
  Pathways:Membrane transporter/Ion channel
  Receptor:TASK-1; TASK-1/TASK-3 heterodimeric; TASK-3
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 2 mg/mL (4.61 mM); Water: 25 mg/mL (57.73 mM); DMSO: 87 mg/mL (200.93 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yost CS. CNS Drug Rev. 2006 Fall-Winter;12(3-4):236-49.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting