• Product NamePentoxifylline
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityA METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.
• Target NameAdenosine Receptor antagonist; PDE inhibitor
• CAS No. 6493-5-6
• Calculated MW 278.31
• Formulation C13H18N4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CN1C=NC2=C1C(=O)N(CCCCC(C)=O)C(=O)N2C
  Pathways:GPCR/G Protein; Metabolism
  Receptor:A2; PDE
  Boling pt:
  Melting pt:98-100C
  Solubility:soluble in Water
  Appearance:White Cotton Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Daly JW, et al. Prog Clin Biol Res. 1987;230:41-63.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting