• Product NamePaliperidone
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityPaliperidone(Invega) is an atypical antipsychotic. Chemically, paliperidone is the primary active metabolite of the older atypical antipsychotic risperidone. It is indicated for the acute and maintenance treatment of schizophrenia.
• Target Name5-HT Receptor antagonist; Adrenergic Receptor antagonist; Dopamine Receptor antagonist; Histamine Receptor antagonist
• CAS No. 144598-75-4
• Calculated MW 426.48
• Formulation C23H27FN4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCC(O)C2=N1
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:5-HT; β-adrenergic receptor; Dopamine; H1 receptor
  Boling pt:612.3C?
  Melting pt:158-160C
  Solubility:DMSO: 4mg/ml(9.38 mM);Water: <1mg/ml;Ethanol: <1mg/ml
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Richelson E, Souder T. Life Sci. 2000 Nov 24;68(1):29-39.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting