• Product NameDantrolene sodium salt
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivitySkeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
• Target NameCalcium Channel inhibitor; Others
• CAS No. 14663-23-1
• Calculated MW 336.23
• Formulation C14H9N4NaO5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:C1C(=O)N=C(N1/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-])[O-].[Na+]
  Pathways:Membrane transporter/Ion channel; Others
  Receptor:Calcium Channel; Ryanodine receptor 1
  Boling pt:85C
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:Orange Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Paul-Pletzer K, et al. J Biol Chem. 2002 Sep 20;277(38):34918-23.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting