• Product NameCetirizine dihydrochloride
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCetirizine dihydrochloride is a potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
• Target NameHistamine Receptor antagonist
• CAS No. 83881-52-1
• Calculated MW 461.81
• Formulation C21H27Cl3N2O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Respiratory system
  SMILES:Cl.OC(=O)COCCN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=C(Cl)C=C1
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:H1 receptor
  Boling pt:
  Melting pt:
  Solubility:Water: 92 mg/mL (199.21 mM); DMSO: 92 mg/mL (199.21 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Christophe B, et al. Eur J Pharmacol. 2003 May 30;470(1-2):87-94.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting